Just updated BobbyMods to 6.11, and for the sites that I set up and manage it was an uneventful affair.
I also updated a couple of multi-site installations, and if you didn't hack core and put the themes and modules where they should go (as opposed to where-ever it works) it should be fairly easy.
For the multi-sites I just keep logging in and performing  and  after the initial update.
If any of the above items above aren't familiar to you, please follow the instructions from the release announcement.
If you don't have the inclination, or don't know what this is all about, just have someone do it for you.
Only you know your install, and when unsure, make a backup of your database and drupal folder before proceeding.